Ampicillin sodium ( Alpen-N, Amcill-S, Ampicillin natrium, Ampicillin sodium )

产品货号. M15658 CAS No. 69-52-3

氨苄西林对于缓解 11 周龄猪的出血性肠炎症状非常有效。

纯度: >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

规格	价格/人民币	库存	数量
1G	￥405	有现货

产品询价大包装询价加入购物车

生物学信息

产品名称

Ampicillin sodium
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

氨苄西林对于缓解 11 周龄猪的出血性肠炎症状非常有效。
产品描述

Ampicillin is very effective in alleviating the symptoms of hemorrhagic enteritis in a 11-week old pig. Ampicillin produces maximum concentrations in bile twice as high as in serum. The peak concentration of ampicillin after an oral dose is as twice as high in portal blood as in peripheral blood. Ampicillin provides neuroprotection against ischemia-reperfusion brain injury. Ampicillin reduces the activities of MMPs and increases the expression level of GLT-1. Pretreatment with ampicillin significantly reduces medial hippocampal cell death following global forebrain ischemia.(In Vitro):Ampicillin inhibits the growth of E. coli of swine origin in a dose-dependent manner. The effective inhibitory concentration of Ampicillin was 2.5 uG/mL.(In Vivo):Ampicillin is very effective in alleviating the symptoms of hemorrhagic enteritis in a 11-week old pig. Ampicillin produces maximum concentrations in bile twice as high as in serum. The peak concentration of ampicillin after an oral dose is as twice as high in portal blood as in peripheral blood. Ampicillin provides neuroprotection against ischemia-reperfusion brain injury. Ampicillin reduces the activities of MMPs and increases the expression level of GLT-1. Pretreatment with ampicillin significantly reduces medial hippocampal cell death following global forebrain ischemia.
体外实验

Ampicillin inhibits the growth of E. coli of swine origin in a dose-dependent manner. The effective inhibitory concentration of Ampicillin was 2.5 uG/mL.
体内实验

Ampicillin is very effective in alleviating the symptoms of hemorrhagic enteritis in a 11-week old pig. Ampicillin produces maximum concentrations in bile twice as high as in serum. The peak concentration of ampicillin after an oral dose is as twice as high in portal blood as in peripheral blood. Ampicillin provides neuroprotection against ischemia-reperfusion brain injury. Ampicillin reduces the activities of MMPs and increases the expression level of GLT-1. Pretreatment with ampicillin significantly reduces medial hippocampal cell death following global forebrain ischemia.
同义词

Alpen-N, Amcill-S, Ampicillin natrium, Ampicillin sodium
通路

GPCR/G Protein
靶点

Antibacterial
受体

β-Lactamase
研究领域

Infection
适应症

——

化学信息

CAS Number

69-52-3
分子量

371.39
分子式

C16H18N3N/AO4S
纯度

>98% (HPLC)
溶解度

DMSO:37 mg/mL (99.62 mM); Ethanol:74 mg/mL (199.25 mM); Water:74 mg/mL (199.25 mM)
SMILES

N(C(=O)[C@@H](c1ccccc1)N)[C@H]1[C@@H]2N(C1=O)[C@H](C(S2)(C)C)C(=O)[O-].[Na+]
化学全称

4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-((aminophenylacetyl)amino)-3,3-dimethyl-7-oxo-, monosodium salt, (2S-(2alpha,5alpha,6beta(S*)))-

运输与储存

储存条件

(-20℃)
运输条件

With Ice Pack
稳定性

≥ 2 years

参考文献

1. Chopra SL, et al. Effect of Ampicillin on E. Coli of Swine Origin. Can J Comp Med Vet Sci. 1963 Sep;27(9):223-7. 2. Lund B, et al. Ampicillin in portal and peripheral blood and bile after oral administration of ampicillin andpivampicillin. Eur J Clin Pharmacol. 1974;7(2):133-5. 3. Lee KE, et al. The neuroprotective mechanism of ampicillin in a mouse model of transient forebrain ischemia. Korean J Physiol Pharmacol. 2016 Mar;20(2):185-92.

计算器

浓度计算器

摩尔计算器

分子量计算器

产品手册